Approach to the differential diagnosis of gastrointestinal polyps:
- When a gastrointestinal polyp is discovered, consideration should be given to an underlying polyposis syndrome
— Adenomatous polyps
— Familial polyposis syndrome
— Turcot syndrome (associated with glioblastoma)
— Hamartomatous polyps
— Basal cell nevus syndrome (associated with medulloblastoma)
— Cowden syndrome
— Cronkhite-Canada syndrome
— Peutz-Jeghers syndrome - Juvenile polyps are usually found in isolation
- Pseudopolyps in colon may be seen in the end stage of ulcerative colitis and are actually normal mucosa surrounded by denuded ulcerated mucosa
- Pseudopolyps in terminal ileum are due to lymphoid hyperplasia