Young adult with sickle cell disease and a headache

CT of calvarial thickening due to marrow hyperplasia in a patient with sickle cell disease
Axial (above left), coronal (above right) and sagittal (below) CT without contrast of the skull shows diffuse massive thickening of the diploic space of the skull.

The diagnosis was calvarial thickening due to marrow hyperplasia in a patient with sickle cell disease.