Former 31 week premature newborn now 3 days old with apnea and bradycardia

US, CT and MRI of Herpes simplex virus-2 encephalitis
Coronal US of the brain (above left) shows increased periventricular echogenicity around the anterior horns of the lateral ventricles with cystic change on the right. Axial CT without contrast of the brain (above right) shows diffuse low density throughout the brain with loss of gray matter white matter differentiation and high density hemorrhage in the posterior horn of the left lateral ventricle and in the right basal ganglia. Coronal (below right) and axial (below left) T2 MRI of the brain show diffuse necrosis developing in the brain, particularly in the frontal lobes. Intraventricular hemorrhage is again noted and the brain appears to be too smooth in appearance for the gestational age.

The diagnosis was Herpes simplex virus-2 encephalitis.

School ager with back pain and incontinence who has been unable to walk for several weeks

CT and MRI of aneurysmal bone cyst of the spine
Sagittal (above left) and axial (above right) CT without contrast of the cervical spine shows an expansile lytic lesion with a thin margin in the spinous and transverse processes of the T1 vertebral body. There is marked anterolisthesis of T1 on T2. Sagittal T2 MRI without contrast of the cervical spine (below left) shows the anterolisthesis at T1 and T2 causing extreme cord compression while an axial T2 MRI obtained at this level (below right) shows a fluid-fluid level in the lesion to the anterior and right of the vertebral body.

The diagnosis was aneurysmal bone cyst of the spine.

Preschooler with left leg weakness and back pain

MRI of diffuse leptomeningeal glioneuronal tumor
Sagittal T1 MRI without contrast of the spine (above left) shows a focal protruberant intramedullary mass in the spinal cord at C7 and T1 that is hyperintense on sagittal T2 MRI (above center) and that on the sagittal T1 MRI with contrast (above right) enhances minimally. There is also thick leptomeningeal enhancement anterior and posterior to the cervical spine. The sagittal T1 MRI with contrast of the brain (below) shows thick leptomeningeal enhancement of the brain, particularly around the basal cisterns.

The diagnosis was diffuse leptomeningeal glioneuronal tumor.

School ager with left upper eyelid swelling

MRI of dacryoadenitis
Coronal T2 MRI without contrast of the orbit (above left) shows hyperintense signal in a superolateral distribution around the left orbit including the left lacrimal gland. Coronal (above right) and axial (below) T1 MRI with contrast shows bright homogenous enhancement in a superolateral distribution around the left orbit including the left lacrimal gland.

The diagnosis was left dacryoadenitis.

Teenager in motor vehicle accident with back pain

CT of lumbar spine fracture of L1 vertebral body
Sagittal CT without contrast of the lumbar spine (left) shows a compression fracture of the L1 vertebral body with fracture fragments off of the anterior and posterior aspects of the L1 vertebral body and a mild compression fracture of the L3 verebral body. Sagittal T2 MRI without contrast of the lumbar spine (right) shows the posterior fracture fragment off of L1 to be effacing the thecal sac anteriorly and causing compression of the spinal cord. There is also bright signal in the L1 vertebral body secondary to the compression fracture.

The diagnosis was a lumbar spine fracture of L1 vertebral body causing cord compression and a lumbar spine compression fracture of L3 vertebral body.

Preschooler who sustained penetrating trauma to the skull base with a rake

MR myelogram of cerebrospinal fluid leak due to dural tear
Sagittal MR myelogram (above left) shows leakage of hyperintense cerebrospinal fluid into the soft tissues inferior to the cerebellum, which lateralizes to the left side on the coronal MR myelogram (above right). Sagittal T2 MRI without contrast of the brain (below) shows the tear in the linear hypointense dura with the hyperintense cerebrospinal fluid leaking through it just inferior to the tip of the cerebellar tonsil.

The diagnosis was cerebrospinal fluid leak due to a dural tear.

Teenager with back pain after jumping off a truck

CT of thoracic spine fracture dislocation with epidural hematoma and cord compression
Coronal (left) and sagittal (middle) CT without contrast of the spine shows fracture of the T6 and T8 vertebral bodies with displacement at T7-T8. Sagittal T2 MRI without contrast of the spine (right) shows spinal stenosis and cord compression and abnormal cord signal and ligament disruption and an epidural hematoma at T7-T8.

The diagnosis was fracture dislocation of the thoracic spine with a spinal epidural hematoma.

Preschooler with vomiting and headaches

MRI of tectal glioma
Sagittal T1 MRI without contrast of the brain (above left) shows an isointense lesion in the tectum and in the pineal gland which on sagittal FLAIR (above right) appears to shows low signal intensity representing perhaps calcification in its pineal component. The lesion is causing dilation of the third ventricle. Axial T2 MRI (below left) shows dilation of the lateral ventricles and transependymal flow of cerebral spinal fluid. Axial T1 MRI with contrast (below right) shows enhancement in the mass.

The diagnosis was tectal glioma that may also involve the pineal gland.